Uniroid-HC ointment is a short-course treatment for haemorrhoids and anal itching. It combines hydrocortisone to reduce inflammation with cinchocaine to ease pain and itch, and can be applied externally or internally using the nozzle applicator.
Uniroid HC ointmentUniroid-HC ointment is a short-course treatment for haemorrhoids and anal itching. It combines hydrocortisone to reduce inflammation with cinchocaine to ease pain and itch, and can be applied externally or internally using the nozzle applicator.
Uniroid-HC ointment is a rectal ointment. It is used for short-term relief of pain, irritation, and itching linked to haemorrhoids (piles) and pruritus ani (anal itching). It’s designed to be applied directly to the sore area. So, the medicine works where the problem is, rather than doing a full-body tour first. [4]
What makes Uniroid-HC ointment different from many “standard” piles creams is the combination of two jobs in one: hydrocortisone helps calm inflammation and swelling, while cinchocaine helps numb pain and itch. That can be a big deal when symptoms are making you dread the loo. [4]
Uniroid-HC ointment is meant for short courses (up to 7 days). If you keep needing it, or your symptoms don’t behave like typical piles, it’s a sign you need a proper review rather than another round of “let’s hope for the best”.
Prescription treatment for piles and anal itching
Hydrocortisone + cinchocaine in one ointment
Can be used externally and internally with the supplied applicator
Short course only (usually up to 7 days)
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Uniroid-HC ointment is a prescription-strength option for piles (haemorrhoids) and anal itching when symptoms are sore, inflamed, and getting in the way of normal life. This deep dive explains what Uniroid-HC ointment is, what’s in it, how it works, how to use it properly (including the applicator), and the key safety points to know before you start. [1] [2]
It’s written for people who want clear, practical advice in plain UK English, plus references you can click and check. If you’re also the sort of person who reads the leaflet “just in case”, you’re in excellent company. [1] [2]
Uniroid-HC ointment combines hydrocortisone (a mild steroid) and cinchocaine (a local anaesthetic) for short-term symptom relief [4]
It’s usually applied twice daily and after bowel movements, for up to 7 days (unless your prescriber says otherwise) [4]
It can be used for external piles, and can also be used internally using the nozzle applicator [4]
Don’t use it if you may have an infection around the anus (for example, thrush, herpes, or bacterial infection) [4]
Fibre, fluids, and less straining still matter, even with a “stronger” ointment [1] [2]
Overview: Uniroid-HC ointment
Uniroid-HC ointment is for short-term relief of piles and anal itching
It combines hydrocortisone (anti-inflammatory) with cinchocaine (local anaesthetic)
It can be used externally, and internally using the supplied nozzle applicator
It’s not suitable if infection is suspected (for example anal thrush or herpes)
Long-term control still relies on stool-softening habits: fibre, fluids, and less straining
Uniroid-HC ointment is often used when symptoms are inflamed and tender, and you need something that calms the area down quickly. It’s not “strong” in the sense of being a cure-all, but it is more targeted than a basic barrier cream.
The hydrocortisone part helps reduce swelling and irritation. That matters because inflamed tissue is more sensitive, more likely to itch, and more likely to feel sore after a bowel movement. [4]
The cinchocaine part helps with pain and itch by numbing the area. That can make the first few days much more manageable, especially if you’ve been stuck in the loop of “itch ? scratch ? worse itch”. [4]
Uniroid-HC ointment works best when you also tackle the trigger. If constipation and straining are the main cause, you’ll get better results if you soften stools and avoid long toilet sessions. Think of the ointment as the calming hand on your shoulder, not the entire life plan.
Finally, it’s meant for short courses. If you keep needing steroid-containing products, it’s worth checking whether the diagnosis is correct, whether there’s an infection in the mix, or whether you need a different treatment approach. [4]
Active ingredient: Uniroid-HC ointment
Each gram of Uniroid-HC ointment contains hydrocortisone 5 mg and cinchocaine hydrochloride 5 mg. Hydrocortisone is a corticosteroid used topically to reduce inflammation, itching, and weeping in irritated skin and perianal tissue. Cinchocaine is a local anaesthetic that reduces pain and itch by blocking nerve signals in the area. [4]
Uniroid-HC ointment also contains cetostearyl alcohol, which can cause local skin reactions in some people (for example contact dermatitis). [4]
What is Uniroid-HC ointment used for?
Uniroid-HC ointment is indicated primarily for external haemorrhoids, for short-term relief of pain, irritation, and itching (pruritus ani). It can also be used for internal haemorrhoids, using the supplied nozzle applicator. [4]
It’s a symptom-relief treatment. That’s not a bad thing, it’s just the honest job description: it helps settle the flare while you work on the underlying causes like constipation, diarrhoea, pregnancy-related pressure, or prolonged straining.
If your symptoms are not typical for piles (for example heavy bleeding, weight loss, black stools, fever, or severe pain), you should get assessed rather than self-treating repeatedly with steroid products.
How does Uniroid-HC ointment work?
Hydrocortisone reduces inflammation in the local tissue. In piles, inflammation and swelling can make the area tender, itchy, and more likely to bleed. By calming the inflammatory response, hydrocortisone helps reduce swelling and irritation over a few days. [4]
Cinchocaine works by blocking nerve signals from the skin and mucosa, which reduces pain and itching. This tends to feel quicker than the steroid effect, which is why some people notice relief soon after applying. [4]
There’s also a practical “behaviour” effect: if the pain and itch are calmer, you’re less likely to scratch or tense up, which can reduce further irritation. It’s not magic, it’s just your nervous system getting a breather.
If you use the applicator internally, the ointment can coat tissue that’s hard to reach with external creams. That can be useful when symptoms feel internal, or when the main discomfort is during or after bowel movements.
Even with a good ointment, stool habits still matter. Hard stools and straining keep re-injuring the area, so fibre, fluids, and sensible toilet time are part of the treatment, not “optional extras”.
How to use Uniroid-HC ointment
Start by gently washing the anal area with water and patting dry. Apply a small amount of Uniroid-HC ointment to the painful area with a finger, without rubbing hard. Many people find cotton wool kinder than toilet paper while things are sore.
Apply twice daily (morning and evening) and after each bowel movement, or exactly as your prescriber advises. Use the smallest amount that covers the area. More ointment doesn’t mean more benefit, it usually just means more mess. [4]
For internal use, attach the nozzle applicator, insert it fully, squeeze gently from the lower end of the tube while withdrawing, then wash the nozzle thoroughly in warm soapy water before and after each use. [4]
Warnings and precautions: Uniroid-HC ointment
Uniroid-HC ointment is for rectal use only and should be applied only to the anus, rectum region, and surrounding skin. Avoid using it on large areas or for longer than recommended, because topical steroids can thin and damage delicate skin if overused. [4]
Don’t use Uniroid-HC ointment if you have certain infections in the area, including anal thrush (fungal infection), tuberculosis, or most viral skin lesions such as herpes simplex, vaccinia, or chickenpox. Steroids can make infections worse by reducing local immune response. [4]
If you keep needing repeated courses, it’s worth pausing and asking why. Recurrent symptoms can be down to constipation, diarrhoea, or lifestyle triggers, but they can also be a sign the diagnosis needs checking. NICE guidance supports assessment when symptoms persist or recur.[2]
Visual disturbance has been reported with systemic and topical corticosteroids. If you notice blurred vision or other visual changes, seek medical advice and consider eye assessment. [4]
This product contains cetostearyl alcohol, which may cause local skin reactions such as contact dermatitis. If you develop a rash or worsening irritation, stop and get advice. [4]
Side effects: Uniroid-HC ointment
Most people use Uniroid-HC ointment for a short time and tolerate it well. Possible side effects include local skin reactions such as rash, urticaria (hives), or irritation, especially if you’re sensitive to ingredients like cinchocaine or cetostearyl alcohol. [4]
With prolonged or repeated steroid use, skin thinning can occur. That’s one reason treatment is normally limited to 7 days. If you find you’re needing it often, it’s time for a review rather than another course. [4]
Systemic absorption is possible, especially if used on damaged skin, large areas, or for long periods. Rarely, this can contribute to adrenal suppression. This is not common with short courses, but it’s part of why “short term” matters. [4]
Blurred vision has been reported (frequency not known). If it happens, don’t ignore it. Get medical advice. [4]
If you think you’re having a serious allergic reaction (swelling, wheeze, trouble breathing), seek urgent medical help.
Drug interactions: Uniroid-HC ointment
The product information notes that co-treatment with CYP3A inhibitors, including cobicistat-containing products, is expected to increase the risk of systemic corticosteroid side effects. The combination should be avoided unless the benefit outweighs the risk, and patients should be monitored if used together. [4]
In practice, this matters most for people taking certain HIV medicines (some include cobicistat) and some other medicines that strongly affect steroid metabolism. If you’re not sure, tell your prescriber or pharmacist what you take, including OTC products and supplements. [4]
Because Uniroid-HC ointment is used topically and for short periods, significant interactions are uncommon, but the caution exists for a reason. If you’re on long-term interacting medicines, it’s worth flagging before you start.
If you’re using other piles products at the same time, check ingredients to avoid doubling up on local anaesthetics or irritants. Layering lots of products can sometimes make symptoms worse, not better.
FAQ: Uniroid-HC ointment
How quickly does Uniroid-HC ointment work?
Cinchocaine can ease pain and itching fairly quickly because it’s a local anaesthetic. Hydrocortisone tends to help over days as inflammation settles.
How long can I use Uniroid-HC ointment for?
Treatment is usually limited to 7 days. If symptoms persist beyond this, you should speak to a clinician for review.
Is Uniroid-HC ointment for internal or external piles?
It’s mainly used for external haemorrhoids, but it can also be used for internal haemorrhoids using the supplied nozzle applicator.
How do I use the applicator with Uniroid-HC ointment?
Attach the nozzle, insert it fully, squeeze gently while withdrawing, and wash the nozzle in warm soapy water before and after each use.
Can I use Uniroid-HC ointment after every bowel movement?
Yes, the usual directions include applying twice daily and after each bowel movement, unless your prescriber advises a different schedule.
Can I use Uniroid-HC ointment if I’m bleeding?
Small amounts of bright red blood can happen with piles, but bleeding should be assessed if it’s new, heavy, persistent, or you’re unsure of the cause.
Can Uniroid-HC ointment make piles go away permanently?
It helps with symptoms short term. Preventing recurrence usually needs fibre, fluids, and less straining, plus treating constipation or diarrhoea if present.
What should I do if Uniroid-HC ointment stings?
A mild sensation can happen on sore skin, but if it’s strong, worsening, or you develop a rash, stop and seek advice as it may be irritation or allergy.
Can I use Uniroid-HC ointment in pregnancy?
Topical steroids should not be used extensively in pregnancy (large amounts or long periods). A clinician should weigh benefits and risks for your situation.
Can I use Uniroid-HC ointment while breastfeeding?
Hydrocortisone may pass into breast milk. Because systemic absorption is possible, it’s generally advised to use it only if the benefits outweigh risks and after clinical advice.
Is Uniroid-HC ointment safe for children?
It’s not recommended for children under 12 unless directed by a doctor.
What infections mean I shouldn’t use Uniroid-HC ointment?
It’s contraindicated in anal thrush, tuberculosis, and most viral skin lesions including herpes simplex, vaccinia, and chickenpox. If you suspect infection, get assessed first.
Can I use Uniroid-HC ointment if I have herpes?
No. Viral lesions such as herpes simplex are listed as a contraindication. Speak to a clinician for the right treatment.
What if my symptoms keep coming back?
If you need repeated courses, you should get reviewed. Persistent or recurrent symptoms may need a different plan or a check that it’s definitely piles.
Can I use Uniroid-HC ointment with a stool softener?
Often, yes. Managing constipation is a key part of piles care. If you’re unsure what’s suitable for you, ask a pharmacist.
Do I need to change my diet while using Uniroid-HC ointment?
It helps. Fibre and fluids reduce straining and can speed recovery and reduce recurrence risk.
Can I use Uniroid-HC ointment with other piles creams?
Check first. Using multiple products can increase irritation or duplicate ingredients like local anaesthetics.
What if I accidentally use too much Uniroid-HC ointment?
Using more than needed is unlikely to help and may increase irritation. If you’ve used a lot or used it for longer than advised, speak to a clinician.
Does Uniroid-HC ointment affect driving?
No, it has no or negligible influence on the ability to drive and use machines.
When should I seek urgent help for piles symptoms?
Seek urgent help for heavy bleeding, severe pain, fever, feeling very unwell, black stools, or a rapidly worsening lump.
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before starting any new treatment.
How this content was created:
This article was written by our in-house editorial team, drawing on information from trusted sources including the NHS, NICE, and peer-reviewed clinical studies. All content is fact-checked and clinically reviewed by a qualified UK pharmacist to ensure accuracy, clarity, and relevance for a UK audience.
[3] NICE (2026) BNF (British National Formulary): haemorrhoids and anorectal preparations. Available at: https://bnf.nice.org.uk/ (Accessed: 4 March 2026).
